Most of the beginning good results, but did not last long, after the effect of getting worse, and even a more serious nasal congestion, more runny nose, then the patient is often in order to increase the quantity and frequency of Dropping to maintain the original effect, but the nasal congestion is long-term unhealed. The medical examination found that the patient's nasal mucosa, particularly in parts of congestive turbinate swelling and fluid secretion increased significantly diagnosed as drug-induced rhinitis, what is it? It turned out that the net intranasal solution of ephedrine, or have a strong contraction vascular effect. After application, does make nasal vasoconstriction, thereby reducing the turbinate to improve the nose ventilation. However, if overdose, excessive vasoconstriction, duration too long, there will be "anti-jump congestion" phenomenon, so that more turbinate swelling, nose ventilation even worse. If the prolonged use appropriate medications or abuse, can cause pathological changes of nasal mucosa, and affect the normal nasal cilia and autonomic activity, may be secondary hypertrophic rhinitis or atrophic rhinitis. If the long-term, continuous, excessive medication, also give rise to accumulation effect, which induced high blood pressure, arrhythmia and other adverse reactions.
Thus, when to use of ephedrine or intranasal, must be strictly controlled to the indications and be particular about the method of medicate, patients suffering from atrophic rhinitis and newborn stuffy nose are disabled intranasal. Children and the elderly the concentration used in nasal drops may be minor, 0.5% of ephedrine, 0.05% of intranasal, once every 4 to 6 hours a time, each nostril Dropping no more than 3 drops. Adults should not be used in continuation more than 7 days. the patient should supine, shoulder the Ministry of booster when Dropping, the first next looked up, gently press after Dropping the nose, left shaking his head several times, so that liquid to fully reach the lesion, 3 to 5 minutes and then sit.
In addition, some caused by nasal obstruction causes can not be ignored, such as deviation of nasal septum, nasal cavity tumor blocked adenoidal hypertrophy; Another example is heart failure caused by a stuffy nose; Another example is the long-term use of antihypertensive drugs reserpine, anti-arrhythmic drugs Inderal (propranolol) and anti-anxiety, anti-emetics perphenazine and so on, need to be a result of the treatment.
Once suffering from a drug-induced rhinitis, should be discontinued as soon as possible, can use normal saline nose drops. If you have a stuffy nose, difficult withdrawal can take the side of the nasal intermittent withdrawal approach. Can also be used betamethasone, and dexamethasone (dexamethasone) intranasal solution or nasal spray, have the better the effect of mitigate mucosal congestion and edema, so that nasal patency and comfortable. But be aware that the hormone-containing nasal drops should not be long-term use.
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